Yufeng Xia Selected Research

arctigenin

10/2020	Arctigenin disrupts NLRP3 inflammasome assembly in colonic macrophages via downregulating fatty acid oxidation to prevent colitis-associated cancer.
1/2020	Pharmacological activation of ERβ by arctigenin maintains the integrity of intestinal epithelial barrier in inflammatory bowel diseases.
12/2016	Arctigenin functions as a selective agonist of estrogen receptor β to restrict mTORC1 activation and consequent Th17 differentiation.
8/2015	Arctigenin exerts anti-colitis efficacy through inhibiting the differentiation of Th1 and Th17 cells via an mTORC1-dependent pathway.
12/2014	Arctigenin but not arctiin acts as the major effective constituent of Arctium lappa L. fruit for attenuating colonic inflammatory response induced by dextran sulfate sodium in mice.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Yufeng Xia Research Topics

Disease

20	Arthritis (Polyarthritis) 12/2020 - 11/2008
17	Experimental Arthritis 01/2022 - 04/2009
12	Rheumatoid Arthritis 09/2022 - 04/2009
11	Colitis 07/2022 - 12/2014
10	Inflammation (Inflammations) 01/2021 - 04/2009
6	Neoplasms (Cancer) 01/2022 - 03/2015
4	Body Weight (Weight, Body) 03/2015 - 11/2008
3	Breast Neoplasms (Breast Cancer) 02/2020 - 01/2018
3	Keloid 08/2017 - 08/2012
3	Cicatrix (Scar) 01/2013 - 11/2008
2	Colitis-Associated Neoplasms 01/2022 - 10/2020
2	Autoimmune Diseases (Autoimmune Disease) 01/2022 - 01/2017
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2020 - 08/2015
1	Paralysis (Palsy) 09/2022
1	Carcinogenesis 10/2020
1	Ulcerative Colitis 01/2020
1	Diabetic Nephropathies (Diabetic Nephropathy) 12/2019
1	Hypoxia (Hypoxemia) 11/2019
1	Cardiovascular Diseases (Cardiovascular Disease) 09/2018
1	Stomach Neoplasms (Stomach Cancer) 02/2018
1	Neoplasm Metastasis (Metastasis) 02/2018

Drug/Important Bio-Agent (IBA)

8	Dextran SulfateIBA 07/2022 - 12/2014
8	AlkaloidsIBA 01/2022 - 04/2009
8	norisoboldineIBA 01/2022 - 08/2012
7	Pharmaceutical PreparationsIBA 10/2021 - 11/2008
7	CollagenIBA 10/2019 - 11/2008
6	TriterpenesIBA 01/2022 - 11/2008
6	madecassosideIBA 12/2020 - 11/2008
5	Interleukin-17 (Interleukin 17)IBA 01/2022 - 05/2015
5	arctigeninIBA 10/2020 - 12/2014
4	madecassic acidIBA 01/2022 - 01/2017
4	tetrandrineIBA 01/2022 - 05/2018
4	isoquinolineIBA 12/2021 - 01/2016
4	Interleukin-10 (Interleukin 10)IBA 01/2017 - 03/2015
3	Therapeutic UsesIBA 10/2019 - 01/2015
3	CytokinesIBA 10/2019 - 03/2015
3	sinomenineIBA 09/2018 - 05/2015
3	Interleukin-6 (Interleukin 6)IBA 12/2015 - 08/2012
3	ScopoletinIBA 07/2015 - 12/2012
3	SaponinsIBA 03/2015 - 08/2012
2	Butyrates (Butyrate)IBA 12/2020 - 11/2019
2	16S Ribosomal RNAIBA 12/2020 - 11/2019
2	Proteins (Proteins, Gene)FDA Link 02/2020 - 12/2016
2	BerberineIBA 11/2019 - 01/2017
2	morinIBA 11/2018 - 12/2015
2	Biological ProductsIBA 02/2018 - 05/2013
2	CurcuminIBA 01/2018 - 05/2015
2	Mechanistic Target of Rapamycin Complex 1IBA 12/2016 - 08/2015
2	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 10/2016 - 01/2016
2	LipopolysaccharidesIBA 12/2015 - 10/2011
2	Collagen Type II (Type II Collagen)IBA 12/2015 - 11/2008
2	coumarinIBA 12/2013 - 07/2009
1	glycyrrhizae radix et rhizomaIBA 09/2022
1	fuzi drug herbalIBA 09/2022
1	tofacitinibIBA 09/2022
1	Antirheumatic Agents (DMARD)IBA 09/2022
1	EnzymesIBA 01/2022
1	Acetyl Coenzyme A (Acetyl-CoA)IBA 01/2022
1	Diclofenac (SR 38)FDA LinkGeneric 10/2021
1	Dextrans (Dextran)FDA Link 01/2021
1	OccludinIBA 01/2021
1	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amideIBA 01/2021
1	sodium sulfate (sodium bisulfate)FDA LinkGeneric 01/2021
1	Anti-Bacterial Agents (Antibiotics)IBA 12/2020
1	Coenzyme A (CoA)IBA 12/2020
1	Butyric Acid (Butanoic Acid)IBA 12/2020
1	AzoxymethaneIBA 10/2020
1	Fatty Acids (Saturated Fatty Acids)IBA 10/2020
1	InflammasomesIBA 10/2020
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 02/2020
1	Tyrosine Kinase InhibitorsIBA 02/2020
1	AfatinibIBA 02/2020
1	bergeninIBA 12/2019
1	NitratesIBA 11/2019
1	Adrenergic Receptors (Adrenergic Receptor)IBA 10/2019
1	Propranolol (Inderal)FDA LinkGeneric 10/2019
1	Hexamethonium (Hexamethonium Bromide)IBA 10/2019
1	Cholinergic Agents (Cholinergics)IBA 10/2019
1	Adrenergic Agents (Adrenergic Drugs)IBA 10/2019
1	Atropine FDA LinkGeneric 10/2019
1	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 10/2019
1	Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA 10/2019
1	Phentolamine (Z-Max)FDA LinkGeneric 10/2019
1	FlavonoidsIBA 11/2018
1	Biomarkers (Surrogate Marker)IBA 05/2018
1	F-Box ProteinsIBA 02/2018
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 02/2018
1	Freund's AdjuvantIBA 01/2018
1	EmulsionsIBA 01/2018
1	Cyclin-Dependent Kinase 3IBA 01/2018
1	Tamoxifen FDA LinkGeneric 01/2018
1	Competitive Endogenous RNAIBA 01/2018
1	rho GTP-Binding Proteins (rho GTP-Binding Protein)IBA 01/2018
1	3' Untranslated Regions (3' UTR)IBA 01/2018
1	Estrogen ReceptorsIBA 01/2018

Therapy/Procedure

11	Oral Administration 01/2022 - 01/2015
4	Chinese Traditional Medicine (Traditional Chinese Medicine) 09/2022 - 07/2009
4	Therapeutics 01/2018 - 08/2012
3	Intraperitoneal Injections 07/2022 - 01/2011
1	Vagotomy 10/2019